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Image fusion is a process to collect the information of the images of the same scene from the different images with a focus on different objects. The Multi-focus image performs a vital role in image process and visual applications. The multi-focus image fusion could be a technique seeks to provide an effective activity level measurement to produce the clarity of source images. It finds application in various fields such as remote sensing, optical microscopy, medical diagnostics, forensic and defense departments. This paper presents totally different multi-focus image fusion techniques in spatial and frequency domain.